
When using the IK Multimedia iRig Keys IO 49 to control Omnisphere, the knobs on the iRig Keys IO 49 are assigned to the following Omnisphere parameters:
First Bank:
- Knob 1 (CC#12) – Global Controls Cutoff
- Knob 2 (CC#13) – Global Controls Resonance
- Knob 3 (CC#14) – Global Controls Filter Envelope Amount
- Knob 4 (CC#15) – Global Controls Vibrato Depth
Second Bank:
- Knob 5 (CC#16) – Global Controls Ambience Amount
- Knob 6 (CC#17) – Global Controls Ambience Length
- Knob 7 (CC#18) – Global Controls Unison
- Knob 8 (CC#19) – Global Controls Glide
Setup
To control Omnisphere using the iRig Keys IO 49, you’ll need to do the following:
- Connect the iRig Keys IO 49 to your computer via USB.
- Set up the iRig Keys IO 49 to control Omnisphere.
- Enable the iRig Keys IO 49 as a MIDI input device in the host software you’re using (DAW, Standalone, etc.).
- Activate the iRig Keys IO 49 Hardware Profile in Omnisphere 3 or later.
IRIG KEYS IO 49 SETUP
Omnisphere relies on the factory default settings of the first preset on the iRig Keys IO 49. Typically, the first preset is automatically activated when the iRig Keys IO 49 is turned on. However, you can make sure the first preset is activated by going through the following steps:
- Press the [ALT] button and then the [PRESET] button.
- Rotate the DATA knob until you see ‘F01” displayed.
- Push down on the [DATA] knob to activate preset F01.
HOST CONNECTION
- Open your host (DAW, Standalone, etc.) and make sure the iRig Keys IO 49 is enabled as a MIDI input device.
OMNISPHERE SETUP
- Open Omnisphere and from the header, select the HW menu button.
- From the drop-down menu, select “IK Multimedia > IK Multimedia iRig Keys IO 49” to activate the iRig Keys IO 49 hardware profile.

TROUBLESHOOTING
Not working? Here are some things to try:
- Is your DAW receiving MIDI from the iRig Keys IO 49?
- Make sure your DAW is configured to correctly route the MIDI output of the iRig Keys IO 49 to the MIDI channel assigned to the desired part in Omnisphere.
- If you are using the Omnisphere standalone host, make sure the MIDI output channel of the iRig Keys IO 49 matches the MIDI channel of the Omnisphere Part you want to control.
- Are the knobs on the iRig Keys IO 49 sending the correct MIDI CC messages? A simple way to check this is by using MIDI Monitor by Snoize or recording knob movement in your DAW. Please refer to the top of the page for a list of the MIDI CC# assignments for each knob:
NOTE: If you need to change the MIDI CC assignments, you’ll need to do so from the iRig Keys IO 25 controller. Please refer to the iRig Keys I/O User Manual for more details.
SUPPORT
Still not working? More questions?
Feel free to contact us directly and we can work with you:
Tech Support
888-870-4223 toll free
818-955-8444
Monday – Friday 10AM – 5PM Pacific Time
email: info@spectrasonics.net



